Pharmaceutical Technology Solutions

What We Offer

Custom Development & Manufacturing (CDMO)

Tailored synthesis and scalable production of pharmaceutical intermediates and specialty chemicals, from route design to GMP manufacturing.

Technology Platform

End-to-end support from gram-scale R&D to ton-scale production, backed by advanced facilities and strong quality & EHS systems.

Molecule Commercialization

We support the commercialization of APIs, intermediates, and fine chemicals with global supply, regulatory services, and logistics coordination.

Global Partnership Network

Trusted partner to top pharmaceutical companies, offering innovation support, scale-up, and long-term supply reliability.

End-to-end Solutions

Chemistry Research Unit (CRU)

Discovery Synthetic Chemistry
Leveraging cutting-edge science to deeply understand reaction mechanisms and deliver innovative molecular design solutions.
Discovery Process Chemistry
Designing and optimizing synthetic routes to establish critical parameters for safe, scalable manufacturing processes.
Building Blocks Development
Developing customized high-purity core molecular fragment libraries to enable modular synthesis of complex drug structures.
Solid Form Screen & Selection
Optimizing solid-state properties through polymorph/salt screening to enhance solubility, stability, and bioavailability.
Impurity Study
Identifying, tracing, and controlling process/degradation impurities to meet ICH genotoxicity and safety compliance standards.
Sample Delivery
Providing GLP/GMP-compliant API and intermediate samples to support clients' further development.

Implementation of QBD Concepts

Final Process Development
1. Development of impurity profile-based processes, PMI reduction, and environmentally friendly processes
2. Process parameter optimization
3. Quality Improvement
4. Plant Fitness Assessment
Justification of the Specs of RSM and Intermediates
Study the formation, fate, and purge of impurities from the RSM synthesis, and establish RSM specs based on the purge studies of these impurities in downstream processes.
Quality Risk Assessment
Comprehensive process characterization via DoE studies or OVAT studies, including FMEA, probability, impact, detectability, PAR, and NOR.

JOOE Group will initiate corresponding Lifecycle Management Plans for clients, formulating mid-to-long-term action plans to ensure products

Maintain cost-competitive/commercial production processes continuously
Possess a stable and secure supply chain consistently
Incorporate rational capacity planning
Provide continuous high-quality services to clients

We manage the product lifecycle from three different aspects

Continuous Cost Optimization
Sustainable Supply Chain Management
Capacity Planning

JOOE Group's professional analytical R&D and quality control teams provide clients with comprehensive quality research and stability study services. Our extensive project experience covers method development and optimization, analytical method validation and transfer, physicochemical property studies, structural confirmation and characterization, reference standard qualification, product release, packaging material compatibility studies, stability studies, and the establishment of quality standards. These services are tailored to meet clients' diverse needs throughout all phases of drug development.

New Drug Globalization Platform

Connecting China's Innovation with the World

Innovative drugs are revolutionizing healthcare with targeted mechanisms, enhanced efficacy, and reduced side effects. China's biopharma innovators excel in cutting-edge domains like ADCs (Antibody-Drug Conjugates), BsAbs (Bispecific Antibodies), and RDCs (Radiopharmaceutical Drug Conjugates). ADCs deliver cytotoxic payloads precisely to cancer cells, maximizing tumor elimination. BsAbs engage dual targets to overcome tumor immune evasion. RDCs integrate diagnostics and radiotherapy for theranostic applications. These breakthroughs underscore China's growing leadership in advancing global precision medicine.

Pharmaceutical Solutions